2017

 

Song, E., Jahng, J.W.S., Chong, L.P., Sung, H., Han, M., Luo, C., Wu, D., Boo, S.*, Hinz, B., Cooper, M., Robertson, A., Berger, T., Mak, T.W., George,I., Schulze, P.C., Wang, Y., Xu, A., Sweeney, G. (2017): Lipocalin-2 deficiency attenuates pressure overload-induced heart failure in mice: a role of reduced HMBG1 induced TLR-4 signaling and NLRP3 inflammasome activation. American Journal of Translational Research [PDF]

Niddam, A.F., Ebady, R., Bansal, A., Koehler, A., Hinz, B. and Moriarty, T.J. (2017): Plasma fibronectin stabilizes Borrelia burgdorferi-endothelial interactions under vascular shear stress by a catch bond mechanism. PNAS 114(17):E3490-E3498 [PDF].

Coelho, N.M., Arora, P.D., van Putten, S.M., Boo, S., Petrovic, P., Hinz, B., and McCulloch, C.A. (2017): Discoidin Domain Receptor 1 Mediates Myosin Dependent Collagen Contraction. Cell Reports 18(7):1774-1790 [PDF]

Li, C.X., Talele, N.P., Boo, S., Knee-Walden, E., Koehler, A., Kapus, A., Speight, P., Balestrini, J.L., Hinz, B. (2017). Micro RNA-21 preserves the fibrotic mechanical memory of mesenchymal stem cells. Nature Materials 16(3): 379-389 [PDF]

2016

 Spinale, F.G., Frangogiannis, N.G., Hinz, B., Holmes, J.W., Kassiri, Z., Lindsey, M.L. (2016): Crossing Into the Next Frontier of Cardiac Extracellular Matrix Research. Circulation Research 119(10):1040-1045  [PDF]

Langevin, H., Keely, P., Mao, J., Hodge, L., Schleip, R., Deng, G., Hinz, B., Swartz, M., de Valois, B., Zick, S., and Findley, T. (2016): Connecting (t)issues: How research in fascia biology can impact integrative oncology. Cancer Research 76(21):6159-6162 [PDF]

Dadson, K., Kovacevic, V., Rengasamy, P., Kim, G.H.E., Boo, S.*, Li, R.K., George, I..P. Schulze, C., Hinz, B., Sweeney, G. (2016) Cellular, structural and functional cardiac remodeling following pressure overload and unloading. International Journal of Cardiology 216:32-42 [PDF]

Hinz, B. (2016): The role of myofibroblasts in wound healing. Current Research in Translational Medicine 64:171-177

Szeto, S.G., Narimatsu, M., Lu, M., He, X., Sidiqi, A.M., Tolosa, M.F., Chan, L., De Freitas, K., Bialik, J.F., Majumder, S., Boo, S., Hinz, B., Dan, Q., Advani, A., John, R., Wrana, J.L., Kapus, A., and Yuen, D.A. (2016) YAP/TAZ are mechanoregulators of TGF-β-Smad signaling and renal fibrogenesis. J Am Soc Nephrol (e-pub ahead of print) [PDF]

Varney, S.D, Betts, C.B., Zheng, R, Wu, L., Hinz, B., Zhou, J., Van De Water, L (2016) Hic-5 is required for myofibroblast differentiation by regulating mechanically dependent, MRTF-A nuclear accumulation. J Cell Sci 129:774-87  [PDF]

Freeman, S.A., Goyette, J., Furuya, W., Woods,E.C., Bertozzi, C.R., Hinz, B., van der Merwe, A.P., Grinstein, S. (2016) Integrins form an expanding diffusional barrier that coordinates phagocytosis. Cell 164(1-2):128-40 [PDF]

Nanchahal, J. and Hinz, B. (2016) Strategies to overcome the hurdles to treat fibrosis, a major unmet clinical need. Proceedings of the National Academy of Science 113(27):7291-3. [PDF]

Bochaton, M.-L., Gabbiani, G., and Hinz, B. (2016) The Myofibroblast in Wound Healing and Fibrosis: Answered and Unanswered Questions. F1000 Research (F1000 Faculty Rev) 5: 752 [PDF]

Hinz, B. and Suki, B. (2016) Does breathing amplify fibrosis? (Editorial on: "AR Froese, C Shimbori, P-S Bellaye, K Ask, M Inman, S Obex, S Fatima, G Jenkins, J Gauldie, and M Kolb, 2016: Stretch Induced Activation of TGF-β1 in Pulmonary Fibrosis"). Am J Resp Crit Care Med 194(1):9-11 [PDF]

Hinz, B. (2016) Myofibroblasts, Experimental Eye Research 142:56-70 [PDF]

 

2015

Hinz, B. (2015) The extracellular matrix and transforming growth factor beta-1: Tale of a strained relationship, Matrix Biology47: 54-65

Talele, N., Fradette, J., Davies, J.E., Kapus, A., and Hinz, B (2015). Expression of α-smooth muscle actin determines the fate of mesenchymal stromal cells. Stem Cell Reports 4, 1016–1030 (Journal Cover Page) [PDF]

Majd, H., Scherer, S.S, Boo, S., Ramondetti, S., Cambridge, E., Raffoul, W., Friedrich, M., Pittet, B., Pioletti D., Hinz, B. (co-corresponding author), and Pietramaggiori, G.*: (2015) Novel micropatterns mechanically control fibrotic reactions at the surface of silicone implants. Biomaterials 54, 136-147 [PDF]

Van Putten, S., Shafieyan, Y., Hinz, B. (2015) Mechanical control of cardiac myofibroblasts, Journal of Molecular and Cellular Cardiology 93, 133-142

Piersma, B., de Rond, S., Werker, P.M.N., Boo, S., Hinz, B. van Beuge, M.M., Bank, R.A. (2015) YAP1 is a driver of myofibroblast differentiation in normal and diseased fibroblasts. Am J Pathol 185, 3326-3337 [PDF]

Mohammadi, H., Pinto, V., Wang, Y., Hinz, B., Janmey, P.A., McCulloch, C.A. (2015) Filamin A Mediates Wound Closure by Promoting Elastic Deformation and Maintenance of Tension in the Extracellular Matrix. J Invest Dermatol 135, 2852-2861 [PDF]

Tobalem, M., Modarressi, A., Lévigne, D., Atashi, F. Villard, F., Hinz, B., Pittet-Cuenod, B. (2015) Hyperglycemia Interacts with Ischemia in a Synergistic Way on Wound Repair and Myofibroblast Differentiation Plastic and Reconstructive Surgery – Global Open 3, e471[PDF]

Dadson, K., Turdi, S., Boo, S., Hinz, B., and Sweeney, G.. (2015) Temporal and molecular analyses of cardiac extracellular matrix remodeling following pressure overload in adiponectin deficient mice PLoS One 10, e0121049  [PDF]

Hinz, B.(2015)Targeting the myofibroblast to improve wound healing. In Wound healing biomaterials, Volume I: „Therapies and regeneration“, Woodhead Publishing Limited, Cambridge, UK, ed.: Magnus S. Ågren”. Springer Science and Business Media Publishing (in press)

Protic, O., P. Toti, M.S. Islam, R. Occhini, S.R. Giannubilo, W.H. Catherino, S. Cinti, F. Petraglia, A. Ciavattini, M. Castellucci, B. Hinz, and P. Ciarmela. (2015). Possible involvement of inflammatory/reparative processes in the development of uterine fibroids. Cell Tissue Res 364(2):415-27 [PDF]

Zimina, E. and Hinz, B. (2015): The stressful life of cardiac myofibroblasts. In: Mechanisms of Cardiac Fibrosis and Heart Failure”. Springer Science and Business Media Publishing, ed: I. Dixon and J. Weigel, 71-92

Balestrini, J. and Hinz, B.: (2015The mechanical regulation of myofibroblasts; mechanically-guided matrix remodeling and prevention of fibrosis in regenerative medicine. In: “Cells, Forces and the Microenvironment”, Pan Stanford Publishing, Singapore, ed. A.E. Pelling and C. M. Cuerrier, 97-113

Shafieyan, Y., Hinz, B. (2015) Signs of stress on soft substrates (Commentary), Journal of Cell Communication and Signaling 9(4), 305-307

 

 

2014

Klingberg, F., Chow, M. L., Koehler, A., Boo, S., Buscemi, L., Quinn, T. M., Costell, M., Alman, B. A., Genot, E., and Hinz, B. (2014). Prestress in the extracellular matrix sensitizes latent TGF-β1 for activation. J Cell Biol 207, 283-297 (Journal Cover Page) [PDF]

Amini-Nik, S., Cambridge, E., Yu, W., Guo, A., Whetstone, H., Nadesan, P., Poon, R., Hinz, B, and Alman, B.A.: (2014) β-catenin is Essential for the Regenerative Capacity of Myeloid Lineage Cells During Wound Repair. Journal of Clinical Investigation 124:2599-2610 [PDF]

Sarrazy, V., Koehler, A., Zimina, Z., Chow, M., Li, C.X., Kato, H., Caldarone, C. A.,and Hinz, B.: (2014) Integrins αvβ3 and αvβ5 contribute to latent TGF-β1 activation by human cardiac fibroblast contraction. Cardiovascular Research 102(3):407-417 [PDF]

Achterberg, V., Buscemi, L (co-first author)*, Diekmann, H., Smith-Clerc, J., Schwengler, H., Lenz, H., Meister, J.-J., Wenck, H., Gallinat, S., and Hinz, B.: (2014) The nano-scale mechanical properties of the extracellular matrix regulate dermal fibroblast function. Journal of Investigative Dermatology 134(7):1862-1872 [PDF]

 

2013

Godbout, C., Follonier Castella, L., Smith, E.A., Talele, N., Chow, M.L., Garonna, A., and Hinz, B.: (2013) The mechanical environment modulates intracellular calcium activities of myofibroblasts. PLoS One 8(5): e64560 [PDF]

Hinz, B.: (2013) It has to be the αv: Latent TGF-β1 activation by myofibroblast integrins. Nature Medicine 19:1567-1568 [PDF]

Kato, H., Fu, Y.Y., Zhu, J., Wang, L., Aafaqi, S., Rahkonen, O., Slorach,C., Traister, A., Leung, C.H., Chiasson, D., Mertens, L., Benson, L., Weisel, R., Hinz, B., Maynes, J.T., Coles, J., Caldarone, C.A. (2013). Pulmonary vein stenosis and the pathophysiology of ‘upstream’ pulmonary veins. Journal of Thoracic and Cardiovascular Surgery 148(1):245-253[PDF]

Hinz, B.: (2013) Matrix mechanics and regulation of the fibroblast phenotype, Periodontology 2000 63, 1–16 [PDF]

Speight, P., Nakano, H., Kelly, T.J., Hinz, B., Kapus, A.: (2013)Differential topical susceptibility to TGFβ in the intact and injured regions of the epithelium: key role in myofibroblast transition. Molecular Biology of the Cell 24:3326-3336[PDF]

Klingberg, F., Hinz, B., White, E.: (2013) The myofibroblast matrix: implications for tissue repair and fibrosis, J Pathology 229:298–309 [PDF]

Gordillo, G., Bernatchez, S., Diegelmann, R., Di Pietro, L., Eriksson, E., Hinz, B. , Hopf, H.W., Kirsner, R., Liu, P., Parnell,L.K.S., Sandusky, G., Sen, C., Tomic-Canic, M., Volk, S., Baird, A:. (2013) Proceedings of the Wound Healing Society pre-conference symposium on pre-clinical models of wound healing: Is man the model? Advances in Wound Care January/February 2013: 1-4 [PDF]

Hinz, B., Ulrich, M., Beele, H., and Kletsas, D.: (2013) The 22nd Annual Meeting of the European Tissue Repair Society, Fibrogenesis & Tissue Repair 6: 3-6 [PDF

 

2012

Balestrini, J.L., Chaudhry, S., Sarrazy, V., Koehler, A., and Hinz, B.: (2012) The mechanical memory of lung myofibroblasts, Integrative Biology 4, 410-421 [PDF]

Hinz, B., Phan, S.H., Thannickal, V.J., Prunotto, M., Desmouliere, A., Varga, J., De Wever, O., Mareel, M., Gabbiani, G.: (2012) Recent developments in myofibroblast biology: paradigms for connective tissue remodeling. American Journal of Pathology 180(4):1340-55 [PDF]

Rosenzweig, D.H., Matmati, M., Khayat, G., Chaudhry, S., Hinz, B., and Quinn, T.M.: (2012) Culture of primary bovine chondrocytes on a continuously expanding surface inhibits dedifferentiation. Tiss Eng Part A 18(23-24):2466-76. [PDF]

Tondeleir, D., Lambrechts, A., Müller, M., Jonckheere, V., Doll, T., Vandamme, D., Bakkali, K., Waterschoot, D., Lemaistre, M., Debeir, O., Decaestecker, C., Hinz, B.: Staes, A., Timmerman, E., Colaert, N., Gevaert, K., Vandekerckhove, J., Ampe, C. (2012)Cells lacking β-actin are genetically reprogrammed and maintain conditional migratory capacity. Mol Cell Proteomics 11: 255-271 [PDF]

Darby, I.A., Hinz, B., and Desmoulière, A.: (2012) Myofibroblasts: Origins and regulation of phenotype by mechanical signaling, Biomedical and Health Research 136-145

Arnoldi, R., Chaponnier, C., and Gabbiani, G., and Hinz, B.: (2012) Smooth muscle heterogeneity, in: Muscle: Fundamental Biology and Mechanisms of Disease, Editors: J. A. Hill & E.N. Olson, 1183-1195

Geissbuehler M., Spielmann T., Formey A., Märki I., Leutenegger M., Hinz B, Johnsson K., Van De Ville D., Lasser T.: (2012) Triplet imaging of oxygen consumption during the contraction of a single smooth muscle cell (A7r5). Adv Exp Med Biol. 737:263-8. [PDF]

Geissbuehler M, Spielmann T., Formey A, Märki I, Leutenegger M, Hinz B, Johnsson K, Van De Ville D, Lasser T.:(2012) Triplet imaging of oxygen consumption during the contraction of a single smooth muscle cell (A7r5). In: “Advances in Experimental Medicine and Biology”, Oxygen Transport to Tissue XXXIII, Springer Science+Business Media, Editors.: Martin Wolf, Hans Ulrich Bucher, Markus Rudin, Sabine Van Huffel, Ursula Wolf, Duane F. Bruley and David K Harrison, 263-268

Hinz, B.: (2012) Mechanical aspects of lung fibrosis: a spotlight on the myofibroblast. Proceedings of the American Thoracic Society 9: 137-147 [PDF].

Hinz, B. and McCulloch, C.M.: (2012) Integrin function in heart fibrosis: Mechanical strain, TGF-β1 activation and collagen glycation, in: “Extracellular matrix: pathobiology and signalling”, edited by Nikos Karamanos, Publisher: DeGruyter, Berlin, Germany, 406-431

Scherer, S.S., Tobalem, M., Vigato, E., Heit, Y., Modarressi, A., Hinz, B., Pittet, B., and Pietramaggiori, G.: (2012)Nonactivated versus thrombin-activated platelets on wound healing and fibroblast-to-myofibroblast differentiation in vivo and in vitro. Plastic and Reconstructive Surgery. 129, 46e-54e [PDF]

Otranto, M., Sarrazy, V., Bonté, F., Hinz, B, Gabbiani, G., Desmoulière, A.: (2012) The role of the myofibroblast in tumor stroma remodeling. Cell Adhesion & Migration 6: 203-219 [PDF]

Hinz, B., Schürch, W., Seemayer, T.A., and Gabbiani, G.: (2012) Myofibroblast. In: “Histology for Pathologists”, 4th edition, S.E. Mills, Lippincott-Williams & Wilkins Pub., USA., 131-177

 

2011

Buscemi, L., Ramonet, D., Klingberg, F., Formey, A., Smith-Clerc, J., Meister, J.-J., and Hinz, B.: (2011) The single-molecule mechanics of the latent TGFβ1 complex. Current Biology 21, 2046–2054 PDF

Carnesecchi, S., Deffert, C., Donati, Y., Basset, O., Hinz, B., Preynat-Seauve, O., Guichard, C., Arbiser, J.L., Banfi, B., Pache, J.-C., Barazzone-Argiroffo, C., Krause, K.-H.: (2011) A key role for NOX4 in epithelial cell death during development of lung fibrosis. Antioxidants and Redox Signaling 15, 607-619 PDF

Hinz, B., Desmoulière, A., Darby, I.A., Gabbiani, G.: (2011) The role of the myofibroblast in fibrosis and cancer progression. In: 'Tumor-Associated Fibroblasts and Their Matrix'. Springer Press, Editors: M. M. Mueller and N. Fusenig, p.37-74 [Publisher]

Hinz, B. and Gabbiani, G.: (2011) The role of myofibroblasts in Dupuytren's disease: Fundamental aspects of contraction and therapeutic perspectives. Book chapter: in "Morbus Dupuytren and Related Hyperproliferative Disorders: Principles, Research, and Clinical Perspectives". Springer Press, Editors: C. Eaton, M. H. Seegenschmiedt, p.53-60 [Publisher]

Majd, H. Quinn, T., Wipff, P.-J., and Hinz, B.: (2011) Dynamic expansion culture for mesenchymal stem cells. 'Mesenchymal Stem Cell Assays and Applications'. Methods in Molecular Biology In: M.C. Vemuri, M.S. Rao & L.G. Chase (eds.), Vol. 698, 175-188  PDF

Obarzanek-Fojt, M., Favre, B., Huber, M., Ryser, S., Moodycliffe, A.M., Wipff, P.-J., Hinz, B., Hohl, D.: (2011) Induction of p38, tumour necrosis factor-α and RANTES by mechanical stretching of keratinocytes expressing mutant keratin 10R156H. British J Dermatol 164, 125-134 PDF

Shieh, A.C. Rozansky, H.A., Hinz, B., Swartz, M.A.: (2011) Tumor cell invasion is promoted by interstitial flow-induced matrix priming by stromal fibroblasts. Cancer Res 71, 790-800 PDF

 

2010

Castella L.F., Buscemi, L., Godbout, C., Meister, J.J., Hinz, B.(2010) A new lock-step mechanism of matrix remodelling based on subcellular contractile events. Journal of Cell Science 123 (10):1751-60 PDF

Castella, L.F., Gabbiani, G., McCulloch, C.A., Hinz, B.(2010) Regulation of myofibroblast activities: Calcium pulls some strings behind the scene. Exp Cell Res. Sep 10;316(15):2390-2401 PDF

Chan, M., Hinz, B., and McCulloch, C.A.: (2010) Mechanical Induction of Gene Expression in Connective Tissue Cells. Gene Expression in Connective Tissue Cells. In: G.V. Shivashankar, editor, Academic Press, Methods in Cell Biology 98. 179-181 PDF

Geissbuehler, M., Spielmann, T., Formey, A., Märki, I., Leutenegger, M., Hinz, B., Johnsson, K., Van De Ville, D., Lasser, T.: (2010) Triplet imaging of oxygen consumption during the contraction of a single smooth muscle cell (A7r5). Biophys J. Jan 20;98(2):339-49 PDF

Hinz, B.(2010) The myofibroblast in connective tissue repair and regeneration In: Regenerative medicine and biomaterials for the repair of connective tissues. Woodhead Publishing, Editors: C. Archer and J. Ralphs, Cardiff, UK, p.39-80 [Publisher]

Hinz, B. and Gabbiani, G.: (2010) Fibrosis: recent advances in myofibroblast biology and new therapeutic perspectives. F1000 Med Rep 2:78 PDF

Hinz, B.(2010) The myofibroblast: Paradigm for a mechanically active cell. J Biomech. Jan 5;43(1):146-55 PDF

Modarressi, A., Pietramaggiori, G., Vigato, E., Godbout, C., Pittet-Cuenod, B., and Hinz, B.: (2010) Hypoxia impairs skin myofibroblast differentiation and function. J Invest Dermatol, 130, 2818-2827 PDF

Obarzanek-Fojt, M., Favre, B., Huber, M., Ryser, S., Moodycliffe, A.M., Wipff, P.-J., Hinz, B., and Hohl, D.: (2010) Induction of p38, tumour necrosis factor-a and RANTES by mechanical stretching of keratinocytes expressing mutant keratin 10R156H. British Association of Dermatologists PDF

Smith-Clerc, J., Hinz, B.: (2010) Immunofluorescence detection of the cytoskeleton and extracellular matrix in tissue and cultured cells. Methods Mol Biol. 611:43-57. PDF

 

2009

Hinz, B.: (2009) Tissue Stiffness, Latent TGFβ1 Activation and Mechanical Signal Transduction: Implications for the Pathogenesis and Treatment of Fibrosis. Current Rheumatology Reports 11:120-6 PDF

Li, B., Bedard, K, Sorce, S., Hinz, B., Dubois-Dauphin, M., Krause, K.-H.: (2009) NOX4 expression in human microglia leads to constitutive generation of reactive oxygen species and to constitutive IL-6 expression. J. Innate Immunity1: 570-581 PDF

Majd, H., Wipff, P.-J., Quinn, T., and Hinz, B.: (2009) A Novel Method of Dynamic Culture Surface Expansion Improves Mesenchymal Stem Cell Proliferation and Phenotype. Stem Cells 27: 200-209 PDF

Smith-Clerc and Hinz, B.: (2009) Visualizing the cytoskeleton - a selection of immunofluorescence protocols. In: T.D. Hewitson, I.A. Darby (eds.), Histology Protocols, Methods in Molecular Biology 611: 43-57

Vaahtomeri, K., Ventelä, E., Laajanen, K., Katajisto, P., Wipff, P.-J., Hinz, B., Vallenius, T., Tiainen, M., Mäkelä., T.P.: (2009)Lkb1 is required for TGFβ-mediated myofibroblast differentiation. J Cell Sci 121:3531-3540 PDF

Wipff, P.-J., Hinz, B.: (2009) Myofibroblasts work best under stress. Journal of Bodywork and Movement Therapies 13, 121–127 PDF

Wipff PJ, Majd H, Acharya C, Buscemi L, Meister JJ, Hinz, B.: (2009) The covalent attachment of adhesion molecules to silicone membranes for cell stretching applications. Biomaterials 30 1781–1789 PDF

 

2008

Acharya, C., Hinz, B., Kundu, S.C.: (2008) The effect of lactose-conjugated silk biomaterials on the development of fibrogenic fibroblasts. Biomaterials. Dec;29(35):4665-75 PDF

Follonier, L., Schaub, S., Meister, J.J., Hinz, B.(2008) Myofibroblast communication is controlled by intercellular mechanical coupling. J Cell Sci. Oct 15;121(Pt 20):3305-16 PDF

Hinz, B.: (2008) Cell adhesion and signaling. In: The motile actin system in health and disease. Edited by C. Ampe and A. Lambrechts, Transworld Research Network, 198-218

Hinz, B.(2008) Molecular regulation of myofibroblast formation. Experimental Dermatology, 17, 873–895 PDF

Machesky, L., Jurdic, P. and Hinz, B.(2008) Grab, stick, pull and digest: the functional diversity of actin-associated matrix-adhesion structures. Workshop on Invadopodia, Podosomes and Focal Adhesions in Tissue Invasion. EMBO reports 9, 139 - 143 PDF

Pittet, P., Lee, K., Kulik, A.J., Meister, J.J., Hinz, B.(2008) Fibrogenic fibroblasts increase intercellular adhesion strength by reinforcing individual OB-cadherin bonds. 1: J Cell Sci. Mar 15;121(Pt 6):877-86 PDF

Vaahtomeri, K., Ventelä, E., Laajanen, K., Katajisto, P., Wipff, P.J., Hinz, B., Vallenius, T., Tiainen, M., Mäkelä, T.P.: (2008) Lkb1 is required for TGFbeta-mediated myofibroblast differentiation. J Cell Sci. Nov 1;121(Pt 21):3531-40 PDF

Wipff, P.J., Hinz, B.: (2008) Integrins and the activation of latent transforming growth factor beta1- an intimate relationship. Eur J Cell Biol. Sep;87(8-9):601-15 PDF

 

2007

Hinz, B., Phan, S.H., Thannickal, V.J., Galli, A., Bochaton-Piallat, M.L., Gabbiani, G.: (2007) The myofibroblast: one function, multiple origins. Am J Pathol. Jun;170(6):1807-16. PDF

Hinz, B.(2007) Formation and function of the myofibroblast during tissue repair. J Invest Dermatol. Mar;127(3):526-37. PDF

Link, A., Vogt, T.K., Favre, S., Britschgi, M.R., Acha-Orbea, H., Hinz, B., Cyster, J.G., Luther, S.A.: (2007) Fibroblastic reticular cells in lymph nodes regulate the homeostasis of naive T cells. Nat Immunol. Nov;8(11):1255-65. PDF

Machesky, L., Jurdic, P., and Hinz, B.: (2007) Grab, stick, pull and digest: the functional diversity of actin-associated matrix adhesion structures. EMBO Reports 9: 139-143. PDF

Schürch, W., Seemayer, T.A., Hinz, B., and Gabbiani, G.: (2007) Myofibroblast. In: Histology for Pathologists. 3rd edition, S.E. Mills, Lippincott-Williams & Wilkins Pub., U.S.A., pp. 123-164. 

Wipff, P.J., Rifkin, D.B., Meister, J.J., Hinz, B.: (2007) Myofibroblast contraction activates latent TGF-beta1 from the extracellular matrix. J Cell Biol. Dec 17;179(6):1311-23. PDF

 

2006

Goffin, J.M., Pittet, P., Csucs, G., Lussi, J., Meister, J.-J., and Hinz, B.(2006) Focal adhesion size controls tension-dependent recruitment of α-smooth muscle actin to stress fibers. J Cell Biol 172: 259-268 (Cover Page) PDF

Hinz, B.: (2006) Masters and servants of the force: the role of matrix adhesions in myofibroblast force perception and transmission. Eur J Cell Biol 85: 175-181

Rönty, M., Leivonen, S.K., Hinz, B., Rachlin, A., Kähäri, V.-M., Otey, C.& Carpén, O.: (2006) Isoform-specific regulation of the actin-organizing protein palladin during TGFβ1-induced myofibroblast differentiation. J Invest Dermatol 126:2387-2395 PDF

Tomasek, J.J., Martin, M.D., Vaughan, M.B., Cowen, R., Kropp, B.P., Gabbiani, G., Haaksma, C.J., and Hinz, B.(2006) Contraction of myofibroblasts in granulation tissue is dependent on Rho/Rho kinase/myosin light chain phosphatase activity. Wound Rep Reg 14:313-320

 

2005

Hinz, B. (co-authorship), Clement, S., Dugina, V., Gabbiani, G., and Chaponnier, C.: (2005) The N‑terminal Ac‑EEED sequence plays a role in alpha-smooth muscle actin incorporation into stress fibers. J Cell Sci 118: 1395-404 PDF

Montjovent, M.O., Mathieu, L., Hinz, B., Applegate, L.L., Bourban, P.-E., Zambelli, P.Y., Manson, J.A., and Pioletti, D.P.: (2005) Biocompatibility of bioresorbable PLA composite scaffolds obtained by supercritical gas foaming with human fetal bone cells. Tissue Eng 11:1640-1649 PDF

Ng, C.P., Hinz, B., and Swartz, M.A.: (2005) Interstitial flow induces myofibroblast differentiation and collagen alignment in vitro. J Cell Sci 118: 4731-4739 PDF

Peters, T., Sindrilaru, A., Hinz, B., Hinrichs, R., Menke, A., Al-Azzeh, E.A.D., Holzwarth, K., Oreshkova, T., Wang, H., Kess, D., Walzog, B., Sulyok, S., Sunderkötter, C., Friedrich, W., Wlaschek, M., Krieg, T., and Scharffetter-Kochanek, K.: (2005) Wound-healing defect of CD18-/- mice due to a decrease in TGF-b1 and myofibroblast differentiation. EMBO J. 24: 3400-3410 PDF

 

2004

Hinz, B., Pittet, P., Smith-Clerc J., Chaponnier, C., and Meister, J.-J.: (2004) Myofibroblast development is characterized by specific cell-cell adherens junctions. Mol Biol Cell 15: 4310-4320 (Cover Page) PDF

Hinz, B.(2004) Discussion of "The contractile properties and responses to tensional loading of Dupuytren's disease-derived fibroblast are altered: a cause of the contracture?" by Bisson et al., Plast Reconstr Surg 13: 622-624

Shepard, P., Hinz, B., Smola-Hess, S., Meister, J.-J., Krieg, T., and Smola, H.: (2004) Dissecting the roles of endothelin and TGFβ in myofibroblast differentiation by keratinocytes. Thromb Haemost 92:262-274

Thorey, I.S., Hinz, B., Hoeflich, A., Kaesler, S., Bugnon, P., Elminger, M., Wanke, R., Wolf, E., and Werner, S.: (2004) Transgenic mice reveal novel activities of growth hormone in wound repair, angiogenesis and myofibroblast differentiation. J Biol Chem 279: 26674-26684 PDF

 

2003

Hinz, B. and Gabbiani, G.: (2003) Cell-matrix and cell-cell contacts of myofibroblasts: role in connective tissue remodeling. Thromb Haemost 90(6):993-1002 (Cover Page)

Hinz, B. and Gabbiani, G.: (2003) Mechanisms of force generation and transmission by myofibroblasts. Curr Opin Biotech 14:538-546 (Cover Page)

Hinz, B., Dugina, V., Ballestrem, C., Wehrle-Haller, B., and Chaponnier, C.: (2003) alpha-smooth muscle actin is crucial for focal adhesion maturation in myofibroblasts. Mol Biol Cell 14: 2508-2519 PDF

 

2002

Hinz, B., Gabbiani, G., and Chaponnier, C.: (2002) The NH2-terminal peptide of alpha-smooth muscle actin inhibits force generation by the myofibroblast in vitro and in vivo. J Cell Biol 157:657-663 PDF

Tomasek, J.J., Gabbiani, G., Chaponnier, C., Hinz, B., and Brown, R.A.: (2002) Myofibroblasts and mechano-regulation of connective tissue remodelling. Nat Rev Mol Cell Biol 3: 349-363 (Cover Page)

 

2001

Ballestrem, C., Hinz, B., Imhof, B., and Wehrle-Haller, B.: (2001) Marching at the front and dragging behind: differential alpha v beta 3 integrin turnover regulates focal adhesion behavior. J Cell Biol 155:1319-1332 PDF

Hinz, B., Celetta, G., Tomasek, J.J., Gabbiani, G., and Chaponnier, C.: (2001) Alpha-smooth muscle actin expression up-regulates fibroblast contractile activity. Mol Biol Cell 12: 2730-2741. PDF

Hinz, B., Mastrangelo, D., Iselin, C.E. Chaponnier, C., and Gabbiani, G.: (2001) Mechanical tension controls granulation tissue contractile activity and myofibroblast differentiation. Am J Pathol 159:1009-1020. (Cover Page) PDF

Hinz, B., von Hänisch, W., Johnen, C., and Kaiser, H.W.: (2001) Das Zytoskelett. In: Fortschritte der Praktischen Dermatologie und Venerologie. edited by G. Plewig and K. Degitz Springer Verlag, 2001. PDF

 

1995 to 2000

Alt, W., O. Brosteanu, Hinz, B., and Kaiser, H.W.: (1995) Patterns of spontaneous motility in videomicrographs of human epidermal keratinocytes. Biochem Cell Biol 73:441-459. [Abstract] PDF

Ballestrem, C., Hinz, B., Wehrle-Haller, B., and Imhof, B.A.: (2000) Actin-dependent lamellipodia formation and microtubule-dependent tail retraction control directed cell migration. Mol Biol Cell 11:2999-3012.  PDF

Hinz, B., Alt, W., Johnen, C., Herzog, V. and Kaiser, H.W.: (1999) Quantifying lamella dynamics of cultured cells by SACED, a new computer-assisted motion analysis. Exp Cell Res 251:234-243. PDF

Hinz, B., and Brosteanu, O.: (1997) Periodicity in shape changes of human epidermal keratinocytes. In: Dynamics of Cell and Tissue Motion, edited by Alt, W., Deutsch, A., and Dunn, G. Basel: Birkhaeuser, p. 15-20. PDF